The developmentally timed decay of an essential microRNA family is seed-sequence dependent

MicroRNA (miRNA) abundance is tightly controlled by regulation of biogenesis and decay. Here, we show that the mir-35 miRNA family undergoes selective decay at the transition from embryonic to larval development in C. elegans. The seed sequence of the miRNA is necessary and largely sufficient for th...

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Detalles Bibliográficos
Autores principales: Donnelly, Bridget F., Yang, Bing, Grimme, Acadia L., Vieux, Karl-Frédéric, Liu, Chen-Yu, Zhou, Lecong, McJunkin, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413084/
https://www.ncbi.nlm.nih.gov/pubmed/35947946
http://dx.doi.org/10.1016/j.celrep.2022.111154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413084/
https://www.ncbi.nlm.nih.gov/pubmed/35947946
http://dx.doi.org/10.1016/j.celrep.2022.111154

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