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Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes

In 2019, synthetic cannabinoids accounted for more than one-third of new drugs of abuse worldwide; however, assessment of associated health risks is not ethical for controlled and often illegal substances, making CD-1 mouse exposure studies the gold standard. Interpretation of those findings then de...

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Detalles Bibliográficos
Autores principales: Crosby, Samantha V., Ahmed, Izzeldin Y., Osborn, Laura R., Wang, Zeyuan, Schleiff, Mary A., Fantegrossi, William E., Nagar, Swati, Prather, Paul L., Boysen, Gunnar, Miller, Grover P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413144/
https://www.ncbi.nlm.nih.gov/pubmed/36005645
http://dx.doi.org/10.3390/metabo12080773