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Comprehensive Analysis of Chromatin Accessibility and Transcriptional Landscape Identified BRCA1 Repression as a Potential Pathological Factor for Keloid

Keloid is a poorly understood fibrotic skin disease that commonly occurs during wound-healing. As a polymer composed of nucleic acid and proteins, the structure of chromatin could be dynamically regulated in the nucleus. In this study, we explored the dynamics of chromatin accessibility and the tran...

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Detalles Bibliográficos
Autores principales: Xie, Kuixia, Yang, Jingrun, Yao, Qianqian, Xu, Yang, Peng, Yonglin, Liu, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413150/
https://www.ncbi.nlm.nih.gov/pubmed/36015648
http://dx.doi.org/10.3390/polym14163391