Hyperbaric oxygen facilitates teniposide-induced cGAS-STING activation to enhance the antitumor efficacy of PD-1 antibody in HCC

BACKGROUND: Emerging evidence indicates that the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) axis plays a pivotal role in intrinsic antitumor immunity. Previous studies demonstrate that the conventional chemotherapy agent, teniposide, effectively promotes the therapeutic effi...

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Detalles Bibliográficos
Autores principales: Li, Kun, Gong, Yihang, Qiu, Dongbo, Tang, Hui, Zhang, Jian, Yuan, Zenan, Huang, Yingqi, Qin, Yunfei, Ye, Linsen, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413187/
https://www.ncbi.nlm.nih.gov/pubmed/36002188
http://dx.doi.org/10.1136/jitc-2021-004006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413187/
https://www.ncbi.nlm.nih.gov/pubmed/36002188
http://dx.doi.org/10.1136/jitc-2021-004006

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