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Covalent Proteomimetic Inhibitor of the Bacterial FtsQB Divisome Complex

[Image: see text] The use of antibiotics is threatened by the emergence and spread of multidrug-resistant strains of bacteria. Thus, there is a need to develop antibiotics that address new targets. In this respect, the bacterial divisome, a multi-protein complex central to cell division, represents...

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Detalles Bibliográficos
Autores principales: Paulussen, Felix M., Schouten, Gina K., Moertl, Carolin, Verheul, Jolanda, Hoekstra, Irma, Koningstein, Gregory M., Hutchins, George H., Alkir, Aslihan, Luirink, Rosa A., Geerke, Daan P., van Ulsen, Peter, den Blaauwen, Tanneke, Luirink, Joen, Grossmann, Tom N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413201/
https://www.ncbi.nlm.nih.gov/pubmed/35945166
http://dx.doi.org/10.1021/jacs.2c06304