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A compatibility evaluation between the physiologically based pharmacokinetic (PBPK) model and the compartmental PK model using the lumping method with real cases

Pharmacokinetic (PK) modeling is a useful method for investigating drug absorption, distribution, metabolism, and excretion. The most commonly used mathematical models in PK modeling are the compartment model and physiologically based pharmacokinetic (PBPK) model. Although the theoretical characteri...

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Detalles Bibliográficos
Autores principales: Ryu, Hyo-jeong, Kang, Won-ho, Kim, Taeheon, Kim, Jae Kyoung, Shin, Kwang-Hee, Chae, Jung-woo, Yun, Hwi-yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413202/
https://www.ncbi.nlm.nih.gov/pubmed/36034786
http://dx.doi.org/10.3389/fphar.2022.964049