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A compatibility evaluation between the physiologically based pharmacokinetic (PBPK) model and the compartmental PK model using the lumping method with real cases
Pharmacokinetic (PK) modeling is a useful method for investigating drug absorption, distribution, metabolism, and excretion. The most commonly used mathematical models in PK modeling are the compartment model and physiologically based pharmacokinetic (PBPK) model. Although the theoretical characteri...
Autores principales: | Ryu, Hyo-jeong, Kang, Won-ho, Kim, Taeheon, Kim, Jae Kyoung, Shin, Kwang-Hee, Chae, Jung-woo, Yun, Hwi-yeol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413202/ https://www.ncbi.nlm.nih.gov/pubmed/36034786 http://dx.doi.org/10.3389/fphar.2022.964049 |
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