Cargando…

Transcriptomic changes in the large organs in lethal meningococcal shock are reflected in a porcine shock model

BACKGROUND: Fulminant meningococcal sepsis with shock and multiple organ failure is associated with a massive systemic inflammatory response involving solid organs. We have previously established a porcine model of the disease to study pathophysiologic and possible therapeutic strategies. OBJECTIVE:...

Descripción completa

Detalles Bibliográficos
Autores principales: Brusletto, Berit Sletbakk, Hellerud, Bernt Christian, Olstad, Ole Kristoffer, Øvstebø, Reidun, Brandtzaeg, Petter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413276/
https://www.ncbi.nlm.nih.gov/pubmed/36034711
http://dx.doi.org/10.3389/fcimb.2022.908204