Thermodynamic vs. Kinetic Control in Synthesis of O-Donor 2,5-Substituted Furan and 3,5-Substituted Pyrazole from Heteropropargyl Precursor

Elaboration of a convenient route towards donor-substituted pyrazoles from heteropropargyl precursors is challenging due to a number of thermodynamically favorable side reactions (e.g., acetylene–allene isomerization and Glaser homocoupling). In this work, Sonogashira cross-coupling conditions of 4-...

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Detalles Bibliográficos
Autores principales: Muravev, Anton A., Ovsyannikov, Alexander S., Konorov, Gennady V., Islamov, Daut R., Usachev, Konstantin S., Novikov, Alexander S., Solovieva, Svetlana E., Antipin, Igor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413326/
https://www.ncbi.nlm.nih.gov/pubmed/36014420
http://dx.doi.org/10.3390/molecules27165178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413326/
https://www.ncbi.nlm.nih.gov/pubmed/36014420
http://dx.doi.org/10.3390/molecules27165178

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