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A Pseudovirus Nanoparticle-Based Trivalent Rotavirus Vaccine Candidate Elicits High and Cross P Type Immune Response

Rotavirus infection continues to cause significant morbidity and mortality globally. In this study, we further developed the S(60)-VP8* pseudovirus nanoparticles (PVNPs) displaying the glycan receptor binding VP8* domains of rotavirus spike proteins as a parenteral vaccine candidate. First, we estab...

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Detalles Bibliográficos
Autores principales: Xia, Ming, Huang, Pengwei, Tan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413348/
https://www.ncbi.nlm.nih.gov/pubmed/36015223
http://dx.doi.org/10.3390/pharmaceutics14081597