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A Pseudovirus Nanoparticle-Based Trivalent Rotavirus Vaccine Candidate Elicits High and Cross P Type Immune Response
Rotavirus infection continues to cause significant morbidity and mortality globally. In this study, we further developed the S(60)-VP8* pseudovirus nanoparticles (PVNPs) displaying the glycan receptor binding VP8* domains of rotavirus spike proteins as a parenteral vaccine candidate. First, we estab...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413348/ https://www.ncbi.nlm.nih.gov/pubmed/36015223 http://dx.doi.org/10.3390/pharmaceutics14081597 |