Validation of CRISPR targeting for proliferation and cytarabine resistance control genes in the acute myeloid leukemia cell line MOLM-13

Acute myeloid leukemia patients with FMS-like tyrosine kinase 3–internal tandem duplications and mixed lineage leukemia–protein AF9 fusion proteins suffer from poor clinical outcomes. The MOLM-13 acute myeloid leukemia cell line harbors both of these abnormalities and is used in CRISPR experiments t...

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Detalles Bibliográficos
Autores principales: Prajapati, Subhash C, Dunham, Nicholas, Fan, Hao, Garrett-Bakelman, Francine E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413368/
https://www.ncbi.nlm.nih.gov/pubmed/35119307
http://dx.doi.org/10.2144/btn-2021-0089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413368/
https://www.ncbi.nlm.nih.gov/pubmed/35119307
http://dx.doi.org/10.2144/btn-2021-0089

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