Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain

Although opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are the most common drugs used in persistent pain treatment; they have shown many side effects. The development of new analgesics endowed with mu opioid receptor/delta opioid receptor (MOR/DOR) activity represents a promising alterna...

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Detalles Bibliográficos
Autores principales: Turnaturi, Rita, Chiechio, Santina, Pasquinucci, Lorella, Spoto, Salvatore, Costanzo, Giuliana, Dichiara, Maria, Piana, Silvia, Grasso, Margherita, Amata, Emanuele, Marrazzo, Agostino, Parenti, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413390/
https://www.ncbi.nlm.nih.gov/pubmed/36014375
http://dx.doi.org/10.3390/molecules27165135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413390/
https://www.ncbi.nlm.nih.gov/pubmed/36014375
http://dx.doi.org/10.3390/molecules27165135

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