Breaking the Iron Homeostasis: A “Trojan Horse” Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition

[Image: see text] Poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors are used in ovarian cancer treatment and have greatly improved the survival rates for homologous recombination repair (HRR)-deficient patients. However, their therapeutic efficacy is limited in HRR-proficient ovarian c...

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Detalles Bibliográficos
Autores principales: Li, Yangyang, Cen, Yixuan, Fang, Yifeng, Tang, Sangsang, Li, Sen, Ren, Yan, Zhang, Hongbo, Lu, Weiguo, Xu, Junfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413404/
https://www.ncbi.nlm.nih.gov/pubmed/35920396
http://dx.doi.org/10.1021/acsnano.2c04956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413404/
https://www.ncbi.nlm.nih.gov/pubmed/35920396
http://dx.doi.org/10.1021/acsnano.2c04956

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