Cargando…

Breaking the Iron Homeostasis: A “Trojan Horse” Self-Assembled Nanodrug Sensitizes Homologous Recombination Proficient Ovarian Cancer Cells to PARP Inhibition

[Image: see text] Poly(adenosine diphosphate-ribose) polymerase (PARP) inhibitors are used in ovarian cancer treatment and have greatly improved the survival rates for homologous recombination repair (HRR)-deficient patients. However, their therapeutic efficacy is limited in HRR-proficient ovarian c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Yangyang, Cen, Yixuan, Fang, Yifeng, Tang, Sangsang, Li, Sen, Ren, Yan, Zhang, Hongbo, Lu, Weiguo, Xu, Junfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413404/ https://www.ncbi.nlm.nih.gov/pubmed/35920396 http://dx.doi.org/10.1021/acsnano.2c04956

Ejemplares similares

Arsenic compound sensitizes homologous recombination proficient ovarian cancer to PARP inhibitors
por: Xu, Junfen, et al.
Publicado: (2021)

Nanoengineered Gallium Ion Incorporated Formulation for Safe and Efficient Reversal of PARP Inhibition and Platinum Resistance in Ovarian Cancer
por: Li, Yangyang, et al.
Publicado: (2023)

Invisible Trojan-horse attack
por: Sajeed, Shihan, et al.
Publicado: (2017)

HIV and Mature Dendritic Cells: Trojan Exosomes Riding the Trojan Horse?
por: Izquierdo-Useros, Nuria, et al.
Publicado: (2010)

Single-Cell RNA Sequencing Reveals the Tissue Architecture in Human High-Grade Serous Ovarian Cancer
por: Xu, Junfen, et al.
Publicado: (2022)

When plants are Trojan horses for viruses
por: Sáez, Cristina, et al.
Publicado: (2022)

Prairie Dog: Cuddly Pet or Trojan Horse?
por: Azad, Abdu F.
Publicado: (2004)

Siderophores as “Trojan Horses”: tackling multidrug resistance?
por: de Carvalho, Carla C. C. R., et al.
Publicado: (2014)

Publisher Correction: Invisible Trojan-horse attack
por: Sajeed, Shihan, et al.
Publicado: (2017)

Trojan‐Horse‐Like Stimuli‐Responsive Microcapsules
por: Mou, Chuan‐Lin, et al.
Publicado: (2018)

Macrophages: a Trojan horse in COVID-19?
por: Park, Matthew D.
Publicado: (2020)

Are Hematologic Patients Trojan Horse for COVID-19?
por: Kılıçaslan, Emrah, et al.
Publicado: (2021)

Macrophages and Monocytes: “Trojan Horses” in COVID-19
por: Percivalle, Elena, et al.
Publicado: (2021)

Trojan Horse‐Like Nano‐AIE Aggregates Based on Homologous Targeting Strategy and Their Photodynamic Therapy in Anticancer Application
por: Li, Yin, et al.
Publicado: (2021)

Silicon particles as trojan horses for potential cancer therapy
por: Fenollosa, Roberto, et al.
Publicado: (2014)

The “TROJAN HORSE” of a Dental Visit – Synovial Sarcoma
por: Mortha, Neeharika, et al.
Publicado: (2018)

The Trojan horse - neuroinflammatory impact of T cells in neurodegenerative diseases
por: Sommer, Annika, et al.
Publicado: (2017)

Extracellular Citrate Is a Trojan Horse for Cancer Cells
por: Petillo, Agata, et al.
Publicado: (2020)

Platelets in Viral Infections – Brave Soldiers or Trojan Horses
por: Schrottmaier, Waltraud C., et al.
Publicado: (2022)

Metabolic Reprogramming in Gastric Cancer: Trojan Horse Effect
por: Bin, Yu-Ling, et al.
Publicado: (2022)

Brain gene therapy with Trojan horse lipid nanoparticles
por: Pardridge, William M.
Publicado: (2023)

Targeting SMYD3 to Sensitize Homologous Recombination-Proficient Tumors to PARP-Mediated Synthetic Lethality
por: Sanese, Paola, et al.
Publicado: (2020)

Tyrosine-Phosphorylated Bacterial Proteins: Trojan Horses for the Host Cell
por: Covacci, Antonello, et al.
Publicado: (2000)

Ducks: The “Trojan Horses” of H5N1 influenza
por: Kim, Jeong‐Ki, et al.
Publicado: (2009)

A peptidic hydrogel that may behave as a “Trojan Horse”
por: Castellucci, Nicola, et al.
Publicado: (2013)

Riding the Trojan horse: combating pest insects with their own symbionts
por: Jurkevitch, Edouard
Publicado: (2011)

The “Trojan Horse” Approach to Tumor Immunotherapy: Targeting the Tumor Microenvironment
por: Nelson, Delia, et al.
Publicado: (2014)

Senescence and NFκB: A trojan horse in tumors?
por: Crescenzi, Elvira, et al.
Publicado: (2012)

Lactose as a “Trojan Horse” for Quantum Dot Cell Transport**
por: Benito-Alifonso, David, et al.
Publicado: (2014)

Is tapentadol a potential Trojan horse in the postdextropropoxyphene era in India?
por: Basu, Aniruddha, et al.
Publicado: (2018)

False friends: Phagocytes as Trojan horses in microbial brain infections
por: Santiago-Tirado, Felipe H., et al.
Publicado: (2017)

Infectious Threats, the Intestinal Barrier, and Its Trojan Horse: Dysbiosis
por: Iacob, Simona, et al.
Publicado: (2019)

Neutrophils as Trojan Horse Vehicles for Brucella abortus Macrophage Infection
por: Gutiérrez-Jiménez, Cristina, et al.
Publicado: (2019)

A Trojan Horse for live-cell super-resolution microscopy
por: Beliu, Gerti, et al.
Publicado: (2020)

Wet-Spun Trojan Horse Cell Constructs for Engineering Muscle
por: Quigley, Anita F., et al.
Publicado: (2020)

The equine species as Trojan horse for Borna Disease Virus-1?
por: van der Kolk, J.H.
Publicado: (2019)

The Trojan-horse mechanism: How networks reduce gender segregation
por: Arvidsson, M., et al.
Publicado: (2021)

Plant extracellular vesicles: Trojan horses of cross‐kingdom warfare
por: He, Baoye, et al.
Publicado: (2021)

Alternative RNA Splicing—The Trojan Horse of Cancer Cells in Chemotherapy
por: Mehterov, Nikolay, et al.
Publicado: (2021)

Natural Trojan horse inhibitors of aminoacyl-tRNA synthetases
por: Travin, Dmitrii Y., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_34tl06aksoutkfk51fratftnrn