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Exploring discordant low amyloid beta and high neocortical tau positron emission tomography cases

INTRODUCTION: Neocortical 3R4R (3‐repeat/4‐repeat) tau aggregates are rarely observed in the absence of amyloid beta (Aβ). (18)F‐MK6240 binds specifically to the 3R4R form of tau that is characteristic of Alzheimer's disease (AD). We report four cases with negative Aβ, but positive tau positron...

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Detalles Bibliográficos
Autores principales: Krishnadas, Natasha, Doré, Vincent, Laws, Simon M., Porter, Tenielle, Lamb, Fiona, Bozinovski, Svetlana, Villemagne, Victor L, Rowe, Christopher C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413469/
https://www.ncbi.nlm.nih.gov/pubmed/36051174
http://dx.doi.org/10.1002/dad2.12326