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Development of Alectinib-Suspended SNEDDS for Enhanced Solubility and Dissolution

Alectinib hydrochloride (ALH), a tyrosine kinase inhibitor, is a practically water-insoluble drug classified as BCS class IV. The present study aimed to develop novel suspended self-nanoemulsifying drug delivery system (Su-SNEDDS) to enhance the solubility and dissolution rate. The Su-SNEDDS was pre...

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Detalles Bibliográficos
Autores principales: Park, Eun Ji, Choi, Seung Ah, Min, Kyoung Ah, Jee, Jun-Pil, Jin, Sung Giu, Cho, Kwan Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413510/
https://www.ncbi.nlm.nih.gov/pubmed/36015320
http://dx.doi.org/10.3390/pharmaceutics14081694