Cargando…

Targeting IRE1α-JNK-c-Jun/AP-1-sEH Signaling Pathway Improves Myocardial and Coronary Endothelial Function Following Global Myocardial Ischemia/Reperfusion

Objectives: Endoplasmic reticulum (ER) stress and soluble epoxide hydrolase (sEH) upregulation/activation have been implicated in myocardial ischemia/reperfusion (I/R) injury. We previously reported that ER stress mediates angiotensin II-induced sEH upregulation in coronary endothelium, whether and...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Hong-Mei, Sun, Wen-Tao, Chen, Huan-Xin, He, Guo-Wei, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413556/
https://www.ncbi.nlm.nih.gov/pubmed/36035373
http://dx.doi.org/10.7150/ijms.74533