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The Relative Positioning of B and T Cell Epitopes Drives Immunodominance

Humoral immunity is crucial for protection against invading pathogens. Broadly neutralizing antibodies (bnAbs) provide sterilizing immunity by targeting conserved regions of viral variants and represent the goal of most vaccination approaches. While antibodies can be selected to bind virtually any r...

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Detalles Bibliográficos
Autores principales: Biavasco, Riccardo, De Giovanni, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413633/
https://www.ncbi.nlm.nih.gov/pubmed/36016115
http://dx.doi.org/10.3390/vaccines10081227