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Overview of Research into mTOR Inhibitors

The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that belongs to the phosphoinositide 3-kinase (PI3K)-related kinase (PIKK) family. The kinase exists in the forms of two complexes, mTORC1 and mTORC2, and it participates in cell growth, proliferation, metabolism, and survival. Th...

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Detalles Bibliográficos
Autores principales: Mao, Beibei, Zhang, Qi, Ma, Li, Zhao, Dong-Sheng, Zhao, Pan, Yan, Peizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413691/
https://www.ncbi.nlm.nih.gov/pubmed/36014530
http://dx.doi.org/10.3390/molecules27165295