Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds

Multivalent antigen display is a well-established principle to enhance humoral immunity. Protein-based virus-like particles (VLPs) are commonly used to spatially organize antigens. However, protein-based VLPs are limited in their ability to control valency on fixed scaffold geometries and are thymus...

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Detalles Bibliográficos
Autores principales: Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Lam, Evan, Denis, Kerri St., Boucau, Julie, Barczak, Amy K, Balazs, Alejandro B., Schmidt, Aaron, Lingwood, Daniel, Bathe, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413718/
https://www.ncbi.nlm.nih.gov/pubmed/36032975
http://dx.doi.org/10.1101/2022.08.16.504128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413718/
https://www.ncbi.nlm.nih.gov/pubmed/36032975
http://dx.doi.org/10.1101/2022.08.16.504128

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