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Enhancing antibody responses by multivalent antigen display on thymus-independent DNA origami scaffolds
Multivalent antigen display is a well-established principle to enhance humoral immunity. Protein-based virus-like particles (VLPs) are commonly used to spatially organize antigens. However, protein-based VLPs are limited in their ability to control valency on fixed scaffold geometries and are thymus...
Autores principales: | Wamhoff, Eike-Christian, Ronsard, Larance, Feldman, Jared, Knappe, Grant A., Hauser, Blake M., Romanov, Anna, Lam, Evan, Denis, Kerri St., Boucau, Julie, Barczak, Amy K, Balazs, Alejandro B., Schmidt, Aaron, Lingwood, Daniel, Bathe, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413718/ https://www.ncbi.nlm.nih.gov/pubmed/36032975 http://dx.doi.org/10.1101/2022.08.16.504128 |
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