Analysis of Biologics Molecular Descriptors towards Predictive Modelling for Protein Drug Development Using Time-Gated Raman Spectroscopy

Pharmaceutical proteins, compared to small molecular weight drugs, are relatively fragile molecules, thus necessitating monitoring protein unfolding and aggregation during production and post-marketing. Currently, many analytical techniques take offline measurements, which cannot directly assess pro...

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Detalles Bibliográficos
Autores principales: Itkonen, Jaakko, Ghemtio, Leo, Pellegrino, Daniela, Jokela (née Heinonen), Pia J., Xhaard, Henri, Casteleijn, Marco G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413954/
https://www.ncbi.nlm.nih.gov/pubmed/36015265
http://dx.doi.org/10.3390/pharmaceutics14081639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413954/
https://www.ncbi.nlm.nih.gov/pubmed/36015265
http://dx.doi.org/10.3390/pharmaceutics14081639

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