Factors Affecting the Metabolic Conversion of Ciprofloxacin and Exposure to Its Main Active Metabolites in Critically Ill Patients: Population Pharmacokinetic Analysis of Desethylene Ciprofloxacin

The objective of this prospective study was to examine the exposure to the main active metabolites of ciprofloxacin in critically ill patients and to examine the factors (demographic, laboratory and genetic) that could potentially affect the drug metabolic conversion of ciprofloxacin. The secondary...

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Detalles Bibliográficos
Autores principales: Šíma, Martin, Bobek, Daniel, Cihlářová, Petra, Ryšánek, Pavel, Roušarová, Jaroslava, Beroušek, Jan, Kuchař, Martin, Vymazal, Tomáš, Slanař, Ondřej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413960/
https://www.ncbi.nlm.nih.gov/pubmed/36015253
http://dx.doi.org/10.3390/pharmaceutics14081627

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413960/
https://www.ncbi.nlm.nih.gov/pubmed/36015253
http://dx.doi.org/10.3390/pharmaceutics14081627

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