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pH-Responsive Lipid Nanoparticles Achieve Efficient mRNA Transfection in Brain Capillary Endothelial Cells
The blood–brain barrier (BBB), which is comprised of brain capillary endothelial cells, plays a pivotal role in the transport of drugs from the blood to the brain. Therefore, an analysis of proteins in the endothelial cells, such as transporters and tight junction proteins, which contribute to BBB f...
Autores principales: | Sakurai, Yu, Watanabe, Himeka, Nishio, Kazuma, Hashimoto, Kohei, Harada, Atsuki, Gomi, Masaki, Suzuki, Masayoshi, Oyama, Ryotaro, Handa, Takumi, Sato, Risa, Takeuchi, Hina, Taira, Ryoga, Tezuka, Kenta, Tange, Kota, Nakai, Yuta, Akita, Hidetaka, Uchida, Yasuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9413996/ https://www.ncbi.nlm.nih.gov/pubmed/36015185 http://dx.doi.org/10.3390/pharmaceutics14081560 |
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