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Flow Equations for Free-Flowable Particle Fractions of Sorbitol for Direct Compression: An Exploratory Multiple Regression Analysis of Particle and Orifice Size Influence

HIGHLIGHTS: Mathematical models were used to predict the mass flow rate for fine sorbitol powder. The prediction accuracy of the respective models was the main validity criterion. A simple regression on orifice size was the best for narrow size fractions. For larger size fractions, both orifice and...

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Detalles Bibliográficos
Autores principales: Marushka, Julia, Hurychová, Hana, Šklubalová, Zdenka, Tebbens, Jurjen Duintjer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414053/
https://www.ncbi.nlm.nih.gov/pubmed/36015279
http://dx.doi.org/10.3390/pharmaceutics14081653