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N′-Substituted 4-Phenylpicolinohydrazonamides with Thiosemicarbazone Moiety as New Potential Antitubercular Agents: Synthesis, Structure and Evaluation of Antimicrobial Activity

Three new 4-phenylpicolin derivatives with a thiosemicarbazone structure were synthesized and evaluated for tuberculostatic activity. The compounds were obtained by the condensation of methyl 4-phenylpicolonimidate with the corresponding cycloalkylamino-1-carbothiohydrazides. The (1)H NMR temperatur...

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Detalles Bibliográficos
Autores principales: Gobis, Katarzyna, Szczesio, Małgorzata, Olczak, Andrzej, Mazerant-Politowicz, Ida, Ziembicka, Dagmara, Pacholczyk-Sienicka, Barbara, Augustynowicz-Kopeć, Ewa, Głogowska, Agnieszka, Korona-Głowniak, Izabela, Fruziński, Andrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414056/
https://www.ncbi.nlm.nih.gov/pubmed/36013649
http://dx.doi.org/10.3390/ma15165513