Aβ and Tau Interact with Metal Ions, Lipid Membranes and Peptide-Based Amyloid Inhibitors: Are These Common Features Relevant in Alzheimer’s Disease?

In the last two decades, the amyloid hypothesis, i.e., the abnormal accumulation of toxic Aβ assemblies in the brain, has been considered the mainstream concept sustaining research in Alzheimer’s Disease (AD). However, the course of cognitive decline and AD development better correlates with tau acc...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Natale, Giuseppe, Sabatino, Giuseppina, Sciacca, Michele Francesco Maria, Tosto, Rita, Milardi, Danilo, Pappalardo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414153/
https://www.ncbi.nlm.nih.gov/pubmed/36014310
http://dx.doi.org/10.3390/molecules27165066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414153/
https://www.ncbi.nlm.nih.gov/pubmed/36014310
http://dx.doi.org/10.3390/molecules27165066

Ejemplares similares