Identifying and correcting repeat-calling errors in nanopore sequencing of telomeres

Nanopore long-read sequencing is an emerging approach for studying genomes, including long repetitive elements like telomeres. Here, we report extensive basecalling induced errors at telomere repeats across nanopore datasets, sequencing platforms, basecallers, and basecalling models. We find that te...

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Detalles Bibliográficos
Autores principales: Tan, Kar-Tong, Slevin, Michael K., Meyerson, Matthew, Li, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414165/
https://www.ncbi.nlm.nih.gov/pubmed/36028900
http://dx.doi.org/10.1186/s13059-022-02751-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414165/
https://www.ncbi.nlm.nih.gov/pubmed/36028900
http://dx.doi.org/10.1186/s13059-022-02751-6

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