Cargando…
Identifying and correcting repeat-calling errors in nanopore sequencing of telomeres
Nanopore long-read sequencing is an emerging approach for studying genomes, including long repetitive elements like telomeres. Here, we report extensive basecalling induced errors at telomere repeats across nanopore datasets, sequencing platforms, basecallers, and basecalling models. We find that te...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414165/ https://www.ncbi.nlm.nih.gov/pubmed/36028900 http://dx.doi.org/10.1186/s13059-022-02751-6 |