Methylphenidate Analogues as a New Class of Potential Disease-Modifying Agents for Parkinson’s Disease: Evidence from Cell Models and Alpha-Synuclein Transgenic Mice

Parkinson’s disease (PD) is characterized by dopaminergic nigrostriatal neurons degeneration and Lewy body pathology, mainly composed of α-synuclein (αSyn) fibrillary aggregates. We recently described that the neuronal phosphoprotein Synapsin III (Syn III) participates in αSyn pathology in PD brains...

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Detalles Bibliográficos
Autores principales: Casiraghi, Andrea, Longhena, Francesca, Faustini, Gaia, Ribaudo, Giovanni, Suigo, Lorenzo, Camacho-Hernandez, Gisela Andrea, Bono, Federica, Brembati, Viviana, Newman, Amy Hauck, Gianoncelli, Alessandra, Straniero, Valentina, Bellucci, Arianna, Valoti, Ermanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414221/
https://www.ncbi.nlm.nih.gov/pubmed/36015221
http://dx.doi.org/10.3390/pharmaceutics14081595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414221/
https://www.ncbi.nlm.nih.gov/pubmed/36015221
http://dx.doi.org/10.3390/pharmaceutics14081595

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