PEG Spacer Length Substantially Affects Antibody-Based Nanocarrier Targeting of Dendritic Cell Subsets

Successful cell targeting depends on the controlled positioning of cell-type-specific antibodies on the nanocarrier’s (NC) surface. Uncontrolled antibody immobilization results in unintended cell uptake due to Fc-mediated cell interaction. Consequently, precise immobilization of the Fc region toward...

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Detalles Bibliográficos
Autores principales: Brückner, Maximilian, Fichter, Michael, da Costa Marques, Richard, Landfester, Katharina, Mailänder, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414227/
https://www.ncbi.nlm.nih.gov/pubmed/36015239
http://dx.doi.org/10.3390/pharmaceutics14081614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414227/
https://www.ncbi.nlm.nih.gov/pubmed/36015239
http://dx.doi.org/10.3390/pharmaceutics14081614

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