Identification of Immunogenic MHC Class II Human HER3 Peptides that Mediate Anti-HER3 CD4(+) Th1 Responses and Potential Use as a Cancer Vaccine

The HER3/ERBB3 receptor is an oncogenic receptor tyrosine kinase that forms heterodimers with EGFR family members and is overexpressed in numerous cancers. HER3 overexpression associates with reduced survival and acquired resistance to targeted therapies, making it a potential therapeutic target in...

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Detalles Bibliográficos
Autores principales: Basu, Amrita, Albert, Gabriella K., Awshah, Sabrina, Datta, Jashodeep, Kodumudi, Krithika N., Gallen, Corey, Beyer, Amber, Smalley, Keiran S.M., Rodriguez, Paulo C., Duckett, Derek R., Forsyth, Peter A., Soyano, Aixa, Koski, Gary K., Lima Barros Costa, Ricardo, Han, Heather, Soliman, Hatem, Lee, Marie Catherine, Kalinski, Pawel, Czerniecki, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
https://www.ncbi.nlm.nih.gov/pubmed/34785506
http://dx.doi.org/10.1158/2326-6066.CIR-21-0454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414303/
https://www.ncbi.nlm.nih.gov/pubmed/34785506
http://dx.doi.org/10.1158/2326-6066.CIR-21-0454

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