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The Loss of focA Gene Increases the Ability of Salmonella Enteritidis to Exit from Macrophages and Boosts Early Extraintestinal Spread for Systemic Infection in a Mouse Model

Salmonella Enteritidis (SE) can spread from the intestines to cause systemic infection, mainly involving macrophages. Intramacrophage Salmonella exits and reinfects neighboring cells, leading to severe disease. Salmonella genes involved in exiting from macrophages are not well understood or fully id...

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Detalles Bibliográficos
Autores principales: Gao, Ran, Zhang, Jian, Geng, Haoyu, Wang, Yaonan, Kang, Xilong, Geng, Shizhong, Jiao, Xin’an, Barrow, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414335/
https://www.ncbi.nlm.nih.gov/pubmed/36013975
http://dx.doi.org/10.3390/microorganisms10081557