Lentinan enhances the antitumor effects of Delta-like 1 via neutrophils

BACKGROUND: Selective activation of Delta-like 1 (DLL1)-Notch signaling is a new approach to activate CD8(+) T cell and suppress tumor growth, while the efficacy remains modest. Lentinan (LNT) is a clinically used immunomodulation agent. Thus, we hypothesized that LNT could improve the efficacy of D...

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Detalles Bibliográficos
Autores principales: Xu, Haiyan, Qi, Ziwei, Zhao, Qi, Xue, Jiao, Zhu, Jiaxing, He, Yan, Liu, Guirong, Qin, Songbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414423/
https://www.ncbi.nlm.nih.gov/pubmed/36008793
http://dx.doi.org/10.1186/s12885-022-10011-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414423/
https://www.ncbi.nlm.nih.gov/pubmed/36008793
http://dx.doi.org/10.1186/s12885-022-10011-w

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