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Safety and efficacy profile of Trastuzumab deruxtecan in solid cancer: pooled reanalysis based on clinical trials

PURPOSE: This study aimed to explore the efficiency and safety of the new generation antibody-drug conjugate Trastuzumab deruxtecan (DS-8201a) in treating HER2-positive solid cancers. METHOD: By searching PubMed, Medline and Ovid for all clinical trials related to the safety and efficacy of DS-8201a...

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Detalles Bibliográficos
Autores principales: Xu, Hanyue, Zhang, Hao, Guo, Wen, Zhong, Xi, Sun, Jing, Zhang, Tao, Wang, Zhoufeng, Ma, Xuelei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414434/
https://www.ncbi.nlm.nih.gov/pubmed/36028823
http://dx.doi.org/10.1186/s12885-022-10015-6