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Immunomodulatory Effects of (R)-Sulforaphane on LPS-Activated Murine Immune Cells: Molecular Signaling Pathways and Epigenetic Changes in Histone Markers

The aim of this study was to explore the immunomodulatory effects of the natural enantiomer (R)-Sulforaphane (SFN) and the possible signaling pathways involved in an ex vivo model of LPS-stimulated murine peritoneal macrophages. Furthermore, we studied the epigenetic changes induced by (R)-SFN as we...

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Detalles Bibliográficos
Autores principales: Alcarranza, Manuel, Villegas, Isabel, Muñoz-García, Rocío, Recio, Rocío, Fernández, Inmaculada, Alarcón-de-la-Lastra, Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414446/
https://www.ncbi.nlm.nih.gov/pubmed/36015113
http://dx.doi.org/10.3390/ph15080966