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Roles of Bromodomain Extra Terminal Proteins in Metabolic Signaling and Diseases
BET proteins, which recognize and bind to acetylated histones, play a key role in transcriptional regulation. The development of chemical BET inhibitors in 2010 greatly facilitated the study of these proteins. BETs play crucial roles in cancer, inflammation, heart failure, and fibrosis. In particula...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414451/ https://www.ncbi.nlm.nih.gov/pubmed/36015180 http://dx.doi.org/10.3390/ph15081032 |