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Hydroxylpropyl-β-cyclodextrin as Potential Excipient to Prevent Stress-Induced Aggregation in Liquid Protein Formulations

Due to the growing demand for patient-friendly subcutaneous dosage forms, the ability to increasing protein solubility and stability in formulations to deliver on the required high protein concentrations is crucial. A common approach to ensure protein solubility and stability in high concentration p...

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Detalles Bibliográficos
Autores principales: Stolzke, Tanja, Krieg, Franziska, Peng, Tao, Zhang, Hailong, Häusler, Olaf, Brandenbusch, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414600/
https://www.ncbi.nlm.nih.gov/pubmed/36014329
http://dx.doi.org/10.3390/molecules27165094