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Hydroxylpropyl-β-cyclodextrin as Potential Excipient to Prevent Stress-Induced Aggregation in Liquid Protein Formulations
Due to the growing demand for patient-friendly subcutaneous dosage forms, the ability to increasing protein solubility and stability in formulations to deliver on the required high protein concentrations is crucial. A common approach to ensure protein solubility and stability in high concentration p...
Autores principales: | Stolzke, Tanja, Krieg, Franziska, Peng, Tao, Zhang, Hailong, Häusler, Olaf, Brandenbusch, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414600/ https://www.ncbi.nlm.nih.gov/pubmed/36014329 http://dx.doi.org/10.3390/molecules27165094 |
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