Early Isolates of SARS-CoV-2 Result in Different Pathogenesis in the Transduced Mouse Model of COVID-19

A transduced mouse model of SARS-CoV-2 infection was established using Balb/c mice. This was achieved through the adenovirus-vectored delivery of the hACE2 gene, to render the mice transiently susceptible to the virus. The model was characterised in terms of the dissemination of hACE2 receptor expre...

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Detalles Bibliográficos
Autores principales: Smither, Sophie J., Kempster, Sarah, Priestnall, Simon L., Suárez-Bonnet, Alejandro, Stapleton, Helen, Laws, Thomas R., Ferguson, Deborah, Almond, Neil, Lever, Mark S., Williamson, E. Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414617/
https://www.ncbi.nlm.nih.gov/pubmed/36016391
http://dx.doi.org/10.3390/v14081769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414617/
https://www.ncbi.nlm.nih.gov/pubmed/36016391
http://dx.doi.org/10.3390/v14081769

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