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Experimental Studies Indicate That ST-2223, the Antagonist of Histamine H3 and Dopamine D2/D3 Receptors, Restores Social Deficits and Neurotransmission Dysregulation in Mouse Model of Autism

Altered regulation of neurotransmitters may lead to many pathophysiological changes in brain disorders including autism spectrum disorder (ASD). Given the fact that there are no FDA-approved effective treatments for the social deficits in ASD, the present study determined the effects of chronic syst...

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Detalles Bibliográficos
Autores principales: Eissa, Nermin, Venkatachalam, Karthikkumar, Jayaprakash, Petrilla, Yuvaraju, Priya, Falkenstein, Markus, Stark, Holger, Sadek, Bassem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414676/
https://www.ncbi.nlm.nih.gov/pubmed/36015079
http://dx.doi.org/10.3390/ph15080929