Mesenchymal and stem-like prostate cancer linked to therapy-induced lineage plasticity and metastasis

Bioinformatic analysis of 94 patient-derived xenografts (PDXs), cell lines, and organoids (PCOs) identifies three intrinsic transcriptional subtypes of metastatic castration-resistant prostate cancer: androgen receptor (AR) pathway + prostate cancer (PC) (ARPC), mesenchymal and stem-like PC (MSPC),...

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Detalles Bibliográficos
Autores principales: Han, Hyunho, Wang, Yan, Curto, Josue, Gurrapu, Sreeharsha, Laudato, Sara, Rumandla, Alekya, Chakraborty, Goutam, Wang, Xiaobo, Chen, Hong, Jiang, Yan, Kumar, Dhiraj, Caggiano, Emily G., Capogiri, Monica, Zhang, Boyu, Ji, Yan, Maity, Sankar N., Hu, Min, Bai, Shanshan, Aparicio, Ana M., Efstathiou, Eleni, Logothetis, Christopher J., Navin, Nicholas, Navone, Nora M., Chen, Yu, Giancotti, Filippo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414743/
https://www.ncbi.nlm.nih.gov/pubmed/35385726
http://dx.doi.org/10.1016/j.celrep.2022.110595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414743/
https://www.ncbi.nlm.nih.gov/pubmed/35385726
http://dx.doi.org/10.1016/j.celrep.2022.110595

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