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In Vitro and In Silico Potential Inhibitory Effects of New Biflavonoids from Ochna rhizomatosa on HIV-1 Integrase and Plasmodium falciparum

The aim of this study was to identify bioactive secondary metabolites from Ochna rhizomatosa with potential inhibitory effects against HIV and Plasmodium falciparum. A phytochemical study of O. rhizomatosa root barks resulted in the identification of three new biflavonoids (1–3), along with four kno...

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Detalles Bibliográficos
Autores principales: Messi, Angélique Nicolas, Bonnet, Susan Lucia, Owona, Brice Ayissi, Wilhelm, Anke, Kamto, Eutrophe Le Doux, Ndongo, Joseph Thierry, Siwe-Noundou, Xavier, Poka, Madan, Demana, Patrick H., Krause, Rui W. M., Ngo Mbing, Joséphine, Pegnyemb, Dieudonné Emmanuel, Bochet, Christian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414862/
https://www.ncbi.nlm.nih.gov/pubmed/36015326
http://dx.doi.org/10.3390/pharmaceutics14081701