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SARS-CoV-2 Mutations and Variants May Muddle the Sensitivity of COVID-19 Diagnostic Assays

The performance of diagnostic polymerase chain reaction (PCR) assays can be impacted by SARS-CoV-2 variability as this is dependent on the full complementarity between PCR primers/probes and viral target templates. Here, we investigate the genetic variability of SARS-CoV-2 regions recognized by prim...

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Detalles Bibliográficos
Autores principales: Alkhatib, Mohammad, Carioti, Luca, D’Anna, Stefano, Ceccherini-Silberstein, Francesca, Svicher, Valentina, Salpini, Romina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414863/
https://www.ncbi.nlm.nih.gov/pubmed/36013977
http://dx.doi.org/10.3390/microorganisms10081559