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New Benzimidazoles Targeting Breast Cancer: Synthesis, Pin1 Inhibition, 2D NMR Binding, and Computational Studies

Benzimidazole derivatives are known to be key players in the development of novel anticancer agents. Herein, we aimed to synthesize novel derivatives to target breast cancer. A new series of benzimidazole derivatives conjugated with either six- and five-membered heterocyclic ring or pyrazanobenzimid...

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Detalles Bibliográficos
Autores principales: Nashaat, Samira, Henen, Morkos A., El-Messery, Shahenda M., Eisa, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414874/
https://www.ncbi.nlm.nih.gov/pubmed/36014485
http://dx.doi.org/10.3390/molecules27165245