A Plausible Mechanism for the Iridium-Catalyzed Hydrogenation of a Bulky N-Aryl Imine in the (S)-Metolachlor Process

The hydrogenation of N-(2-ethyl-6-methylphenyl)-1-methoxypropan-2-imine is the largest-scale asymmetric catalytic process for the industrial production of agrochemical (S)-metolachlor. The challenging hydrogenation across the sterically crowded carbon–nitrogen double bond was achieved using a mixtur...

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Detalles Bibliográficos
Autores principales: Kwan, Amanda L., Morris, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414898/
https://www.ncbi.nlm.nih.gov/pubmed/36014344
http://dx.doi.org/10.3390/molecules27165106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414898/
https://www.ncbi.nlm.nih.gov/pubmed/36014344
http://dx.doi.org/10.3390/molecules27165106

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