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Biomaterial-Mediated Protein Expression Induced by Peptide-mRNA Nanoparticles Embedded in Lyophilized Collagen Scaffolds

In our aging society, the number of patients suffering from poorly healing bone defects increases. Bone morphogenetic proteins (BMPs) are used in the clinic to promote bone regeneration. However, poor control of BMP delivery and thus activity necessitates high doses, resulting in adverse effects and...

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Detalles Bibliográficos
Autores principales: Oude Egberink, Rik, Zegelaar, Helen M., El Boujnouni, Najoua, Versteeg, Elly M. M., Daamen, Willeke F., Brock, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414905/
https://www.ncbi.nlm.nih.gov/pubmed/36015245
http://dx.doi.org/10.3390/pharmaceutics14081619