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The Protective Effect of α-Lipoic Acid against Gold Nanoparticles (AuNPs)-Mediated Liver Damage Is Associated with Upregulating Nrf2 and Suppressing NF-κB

This study examined if regulating the keap-1? Nrf2 antioxidant pathway mediated gold nanoparticles (AuNPs) induced liver damage, and examined the protective effect of co-supplement of α-lipoic acid (α-LA). Rats were separated into 4 groups (n = 8/each) as control, α-LA (200 mg/kg), AuNPs (5 µg/2.85...

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Detalles Bibliográficos
Autores principales: Alshammari, Ghedeir M., Abdelhalim, Mohamed Anwar, Al-Ayed, Mohammed S., Al-Harbi, Laila Naif, Yahya, Mohammed Abdo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9414933/
https://www.ncbi.nlm.nih.gov/pubmed/36014833
http://dx.doi.org/10.3390/nu14163327