Inter-Ligand STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket

In recent years, Saturation Transfer Difference NMR (STD NMR) has been proven to be a powerful and versatile ligand-based NMR technique to elucidate crucial aspects in the investigation of protein-ligand complexes. Novel STD NMR approaches relying on “multi-frequency” irradiation have enabled us to...

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Detalles Bibliográficos
Autores principales: Monaco, Serena, Ramírez-Cárdenas, Jonathan, Carmona, Ana Teresa, Robina, Inmaculada, Angulo, Jesus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415034/
https://www.ncbi.nlm.nih.gov/pubmed/36015178
http://dx.doi.org/10.3390/ph15081030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415034/
https://www.ncbi.nlm.nih.gov/pubmed/36015178
http://dx.doi.org/10.3390/ph15081030

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