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Inter-Ligand STD NMR: An Efficient 1D NMR Approach to Probe Relative Orientation of Ligands in a Multi-Subsite Protein Binding Pocket
In recent years, Saturation Transfer Difference NMR (STD NMR) has been proven to be a powerful and versatile ligand-based NMR technique to elucidate crucial aspects in the investigation of protein-ligand complexes. Novel STD NMR approaches relying on “multi-frequency” irradiation have enabled us to...
Autores principales: | Monaco, Serena, Ramírez-Cárdenas, Jonathan, Carmona, Ana Teresa, Robina, Inmaculada, Angulo, Jesus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9415034/ https://www.ncbi.nlm.nih.gov/pubmed/36015178 http://dx.doi.org/10.3390/ph15081030 |
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